Anti-cancer effect of exercise

The anti-cancer effects of exercise are due to increases in a protein that blocks the growth of cancer cells and induces cell death, according to Australian researchers.

The protein, called insulin-like binding protein-3 (IGFBP-3), inhibits another protein called insulin-like growth factor-1 (IGF-1), thereby blocking IGF-1's proliferative effect on cell growth, the study hints.

Analyses centered on 443 colon cancer patients followed for more than 5 years.

Among subjects who were physically active, there was a 48 percent reduction in colon cancer-specific deaths.

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